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Fig. 2 | Cancer Cell International

Fig. 2

From: Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation

Fig. 2

Identification of core targets for HLJDD against OSCC. A The nodes and edges of five networks including OSCC related targets, the potential active ingredients related targets of Phellodendron amurense Rupr, Coptis chinensis Franch, Scutellaria baicalensis Georgi and Gardenia jasminoides J.Ellis. B A merged network. C The core targets screening by degree value. Yellow color represented the core targets. D The protein–protein interaction network of the core targets built by using Search Tool for the Retrieval of Interacting Genes (STRING) (https://string-db.org/). Network nodes represented proteins and edges represented protein–protein associations (Different colors represented that protein–protein interactions validated by different sources)

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