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Table 3 Univariate and multivariate analysis of OS

From: Prognostic value of preoperative inflammatory markers in patients with hepatocellular carcinoma who underwent curative resection

Variable

 

Univariate analysis

Multivariate analysis

 

HR (95%CI)

P value

HR (95%CI)

P value

Sex

Male/female

1.478 (0.912–2.393)

0.113

  

Age (years)

 ≥ 60/ < 60

0.670 (0.451–0.996)

0.048

  

HBsAg

Positive/negative

1.630 (0.940–2.736)

0.083

  

Liver cirrhosis

Yes/no

1.036 (0.742–1.448)

0.834

  

Portal vein invasion

Yes/no

3.757 (2.256–6.256)

 < 0.001

  

Ascites

Yes/no

3.564 (1.804–7.039)

 < 0.001

  

Ablation or TACE

Yes/no

1.047 (0.757–1.449)

0.780

  

AFP (ng/ml)

 > 400/ ≤ 400

1.844 (1.334–2.549)

 < 0.001

  

Tumor capsule

No/yes

2.710 (1.811–4.056)

 < 0.001

2.119 (1.394–3.222)

 < 0.001

Tumor number

 ≥ 2/1

1.893 (1.230–2.915)

0.004

  

Tumor size (cm)

 > 5/ ≤ 5

2.170 (1.553–3.033)

 < 0.001

1.646 (1.157–2.342)

0.006

MVIa

Yes/no

2.084 (1.495–2.906)

 < 0.001

1.678 (1.195–2.355)

0.003

Cell differentiation

Moderate/well

2.718 (1.112–6.647)

0.028

  

Poor/well

3.703 (1.375–9.976)

0.010

  

MKIb

No/yes

0.853 (0.492–1.480)

0.572

  

Child class

B/A

1.380 (0.609–3.126)

0.440

  

NLR

 > 2.37/ ≤ 2.37

1.615 (1.157–2.253)

0.005

  

PLR

 > 117.09/ ≤ 117.09

1.542 (1.115–2.133)

0.009

1.465 (1.024–2.096)

0.037

GPR

 > 0.48/ ≤ 0.48

3.002 (2.131–4.230)

 < 0.001

2.554 (1.757–3.712)

 < 0.001

ALR

 > 31/ ≤ 31

2.255 (1.628–3.122)

 < 0.001

1.553 (1.098–2.197)

0.013

FAR

 > 0.06/ ≤ 0.06

1.984 (1.425–2.764)

 < 0.001

  
  1. aMVI: microvascular invasion
  2. bMKI: multiple kinase inhibitor