|
Variable
| |
Univariate analysis
|
Multivariate analysis
|
|---|
| |
HR (95%CI)
|
P value
|
HR (95%CI)
|
P value
|
|---|
|
Sex
|
Male/female
|
1.478 (0.912–2.393)
|
0.113
| | |
|
Age (years)
|
≥ 60/ < 60
|
0.670 (0.451–0.996)
|
0.048
| | |
|
HBsAg
|
Positive/negative
|
1.630 (0.940–2.736)
|
0.083
| | |
|
Liver cirrhosis
|
Yes/no
|
1.036 (0.742–1.448)
|
0.834
| | |
|
Portal vein invasion
|
Yes/no
|
3.757 (2.256–6.256)
|
< 0.001
| | |
|
Ascites
|
Yes/no
|
3.564 (1.804–7.039)
|
< 0.001
| | |
|
Ablation or TACE
|
Yes/no
|
1.047 (0.757–1.449)
|
0.780
| | |
|
AFP (ng/ml)
|
> 400/ ≤ 400
|
1.844 (1.334–2.549)
|
< 0.001
| | |
|
Tumor capsule
|
No/yes
|
2.710 (1.811–4.056)
|
< 0.001
|
2.119 (1.394–3.222)
|
< 0.001
|
|
Tumor number
|
≥ 2/1
|
1.893 (1.230–2.915)
|
0.004
| | |
|
Tumor size (cm)
|
> 5/ ≤ 5
|
2.170 (1.553–3.033)
|
< 0.001
|
1.646 (1.157–2.342)
|
0.006
|
|
MVIa
|
Yes/no
|
2.084 (1.495–2.906)
|
< 0.001
|
1.678 (1.195–2.355)
|
0.003
|
|
Cell differentiation
|
Moderate/well
|
2.718 (1.112–6.647)
|
0.028
| | |
|
Poor/well
|
3.703 (1.375–9.976)
|
0.010
| | |
|
MKIb
|
No/yes
|
0.853 (0.492–1.480)
|
0.572
| | |
|
Child class
|
B/A
|
1.380 (0.609–3.126)
|
0.440
| | |
|
NLR
|
> 2.37/ ≤ 2.37
|
1.615 (1.157–2.253)
|
0.005
| | |
|
PLR
|
> 117.09/ ≤ 117.09
|
1.542 (1.115–2.133)
|
0.009
|
1.465 (1.024–2.096)
|
0.037
|
|
GPR
|
> 0.48/ ≤ 0.48
|
3.002 (2.131–4.230)
|
< 0.001
|
2.554 (1.757–3.712)
|
< 0.001
|
|
ALR
|
> 31/ ≤ 31
|
2.255 (1.628–3.122)
|
< 0.001
|
1.553 (1.098–2.197)
|
0.013
|
|
FAR
|
> 0.06/ ≤ 0.06
|
1.984 (1.425–2.764)
|
< 0.001
| | |
- aMVI: microvascular invasion
- bMKI: multiple kinase inhibitor
