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Table 3 Univariate and multivariate analysis of OS

From: Prognostic value of preoperative inflammatory markers in patients with hepatocellular carcinoma who underwent curative resection

Variable   Univariate analysis Multivariate analysis
  HR (95%CI) P value HR (95%CI) P value
Sex Male/female 1.478 (0.912–2.393) 0.113   
Age (years)  ≥ 60/ < 60 0.670 (0.451–0.996) 0.048   
HBsAg Positive/negative 1.630 (0.940–2.736) 0.083   
Liver cirrhosis Yes/no 1.036 (0.742–1.448) 0.834   
Portal vein invasion Yes/no 3.757 (2.256–6.256)  < 0.001   
Ascites Yes/no 3.564 (1.804–7.039)  < 0.001   
Ablation or TACE Yes/no 1.047 (0.757–1.449) 0.780   
AFP (ng/ml)  > 400/ ≤ 400 1.844 (1.334–2.549)  < 0.001   
Tumor capsule No/yes 2.710 (1.811–4.056)  < 0.001 2.119 (1.394–3.222)  < 0.001
Tumor number  ≥ 2/1 1.893 (1.230–2.915) 0.004   
Tumor size (cm)  > 5/ ≤ 5 2.170 (1.553–3.033)  < 0.001 1.646 (1.157–2.342) 0.006
MVIa Yes/no 2.084 (1.495–2.906)  < 0.001 1.678 (1.195–2.355) 0.003
Cell differentiation Moderate/well 2.718 (1.112–6.647) 0.028   
Poor/well 3.703 (1.375–9.976) 0.010   
MKIb No/yes 0.853 (0.492–1.480) 0.572   
Child class B/A 1.380 (0.609–3.126) 0.440   
NLR  > 2.37/ ≤ 2.37 1.615 (1.157–2.253) 0.005   
PLR  > 117.09/ ≤ 117.09 1.542 (1.115–2.133) 0.009 1.465 (1.024–2.096) 0.037
GPR  > 0.48/ ≤ 0.48 3.002 (2.131–4.230)  < 0.001 2.554 (1.757–3.712)  < 0.001
ALR  > 31/ ≤ 31 2.255 (1.628–3.122)  < 0.001 1.553 (1.098–2.197) 0.013
FAR  > 0.06/ ≤ 0.06 1.984 (1.425–2.764)  < 0.001   
  1. aMVI: microvascular invasion
  2. bMKI: multiple kinase inhibitor