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Fig. 6 | Cancer Cell International

Fig. 6

From: Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

Fig. 6

Exosomal lncRNA SNHG10 regulated the function of NK cells through INHBC. A The proliferation of NK92-MI cells was detected by CCK-8 assay. B The cytotoxicity of NK92-MI cells was detected by LDH assay. C The production of IFN-γ from NK92-MI cells was detected by ELISA. D The expression of the toxic molecules perforin and granzyme B in NK92-MI cells was measured by western blotting. GAPDH was used to normalize gene expression. The data were analyzed by ANOVA followed by Tukey’s test, *NC vs. oe-lncSNHG10 exo, # NC vs. si-INHBC. *P < 0.05, **P < 0.01, ***P < 0.001, ##P < 0.01, ###P < 0.001

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