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Fig. 7 | Cancer Cell International

Fig. 7

From: Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

Fig. 7

Exosomal lncRNA SNHG10 promoted CRC growth by inhibiting NK cells in vivo. A, B Xenograft tumors of BALB/C mice after injection of LV-lncRNA SNHG10-SW480 and LV-vector-SW480 cells (n = 10 per group). C Tumor volume in the two groups. D Tumor weight of each mouse in the two groups. E, F The levels of the INHBC, perforin, and granzyme B proteins in mice were detected by western blotting. Representative images (G) and statistical analysis (H) of the flow cytometry of NK1.1 in mice in the two groups.I Representative images of IHC of NK1.1 in mice in the two groups. GAPDH was used to normalize gene expression. t-test, *P < 0.05, **P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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