Fig. 8

ENO1 was upregulated in NSCLC and positively correlated with AL355338 expression. A ENO1 expression was analyzed by IHC in NSCLC specimens from 80 patients. Representative images are shown for absent, weak, moderate and strong expression of ENO1. Scale bar, 100 μm. B The distribution of ENO1 expression level in IHC. C A positive correlation between ENO1 and AL355338 expression was observed in NSCLC specimens from 80 patients (R = 0.322, P = 0.008 by Spearman correlation test). D, E The expression pattern of ENO1 in lung adenocarcinoma and lung squamous carcinoma based on TCGA data from GEPIA platform (http://gepia2.cancer-pku.cn). F Kaplan–Meier analysis of overall survival of the 80 patients with NSCLC according to different ENO1 levels. G, H TCGA data from GEPIA Platform further demonstrated that high ENO1 expression indicated poor survival of NSCLC patients