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Fig. 7 | Cancer Cell International

Fig. 7

From: FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway

Fig. 7

FAM49B regulates proliferation and migration of BC cells by upregulating Rab10. scr- or Rab10-shRNA were transfected into FAM49B-overexpressing MCF-7 and MDA-MB-231 cells. Cell growth rate (A) was monitored by MTT assay in MCF-7 and MDA-MB-231 cells (n = 3). B, C Cell migration was examined via wound healing (B) and transwell assays (C) in MDA-MB-231 cells (n = 3). Results are presented as the mean ± SD. The statistical significance was assessed by Student’s t-test; **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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