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Fig. 5 | Cancer Cell International

Fig. 5

From: Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Fig. 5

SNTB1 knockdown inhibits colorectal cancer (CRC) cell growth in vivo. A xenograft nude mouse model was established to investigate the tumor growth of HCT116 (left panel) and RKO (right panel) cells in vivo. A total of 1.0 × 106 transduced cells were injected subcutaneously into the forelimb axillae (sh-Ctrl: left; sh-SNTB1: right) of BALB/c nude mice; these cells had been transduced with lentivirus encoding sh-Ctrl (left axilla) or sh-SNTB1 (right axilla). The tumor volumes (a), fluorescence of GFP (b and c), images of tumor and tumor weights (d and e) were determined and recorded. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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