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Fig. 4 | Cancer Cell International

Fig. 4

From: Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma

Fig. 4

Expression and prognostic value of PLAU-targeted miRNAs in HNSCC. a MiR-181c-5p (p = 0.077, left) and miR-23b-3p (p < 0.001, right) were downregulated in HNSCC compared to normal tissues. b The expression level of miR-23b-3p was negatively correlated with PLAU expression. c Downregulation of miR-23b-3p predicted a worse prognosis in the 5-year survival of patients with HNSCC. d The biological functions and signaling pathways associated with miR-181c-5p and miR-23b-3p were predicted by GO and KEGG pathway analysis

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Cancer Cell International

ISSN: 1475-2867

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