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Table 3 Multivariate Cox regression analysis of prognostic factors of HNSCC

From: Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma

Variable OS
RR 95% CI p-value
Sex (male/female) 0.745 (0.536, 1.038) 0.082
Age, years (≥ 60/ < 60) 0.823 (0.607, 1.117) 0.211
Smoking status (yes/no) 1.065 (0.732, 1.549) 0.742
Tumor stage (T1/T2/T3/T4) 0.865 (0.710, 1.054) 0.150
Lymph metastasis (N0/N1/N2) 1.012 (0.839, 1.221) 0.901
Clinical stage (I/II/III/IV) 1.531 (1.194, 1.963) 0.001*
PLAU expression (high/low) 1.639 (1.216, 2.209) 0.001*
  1. OS overall survival, RR relative risk, CI confidence interval
  2. *p < 0.05