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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA LINC00337 sponges mir-1285-3p to promote proliferation and metastasis of lung adenocarcinoma cells by upregulating YTHDF1

Fig. 5

LINC00337 controls the miR-1285-3p target gene YTHDF1. A Proposed binding sequence of miR-1285-3p with YTHDF1. B YTHDF1 levels in 46 paired lung adenocarcinoma and para-tumor tissues. C The protein levels of YTHDF1 in cells undergoing shRNA or LINC00337 transfection were evaluated by western blot assay, with GAPDH as a standard. D Relative luciferase activities of YTHDF1 3′-UTR reporter in stable A549 and PC-9 cells undergoing shRNA or LINC00337 transfection were examined using the Dual-Luciferase Reporter Assay System. E Relative luciferase activities of YTHDF1 promoter reporter in stable A549 and PC-9 cells receiving shRNA or LINC00337 transfection. F YTHDF1 expression level in stable A549 and PC-9 cells after transfection. Data represent the mean ± SD; ** P < 0.01, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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