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Table 1 Correlation of tissue CPN1 expression with clinicopathological parameters

From: Carboxypeptidase N1 is anticipated to be a synergy metrics for chemotherapy effectiveness and prognostic significance in invasive breast cancer

Parameters

Sample

CPN1

x2

P value

Low

High

Age (years) ≤ 60

77

53

24

2.851

0.091

 > 60

46

23

23

  

Tumor size (cm) ≤ 5

103

67

36

4.325

0.038*

 > 5

20

9

11

  

LN metastasis N0

61

38

23

3.031

0.082

 N1

62

24

38

  

TNM stage I–II

71

49

22

5.083

0.024*

 III–IV

52

26

26

  

 Histological grade I–II

66

48

18

4.389

0.036*

 III

57

32

45

  

ER score ≤ 4

66

39

27

10.557

0.228

 > 4

57

37

20

  

PR score ≤ 4

91

58

33

12.553

0.128

 > 4

32

18

14

  

HER2 score ≤ 4

66

47

19

9.503

0.302

 > 4

57

29

28

  

KI67 score ≤ 4

94

57

37

10.8

0.213

 > 4

29

19

10

  

P53 score ≤ 4

77

47

30

7.97

0.436

 > 4

46

29

17

  
  1. *Statistically significant (P < 0.05)