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Table 1 Correlation of tissue CPN1 expression with clinicopathological parameters

From: Carboxypeptidase N1 is anticipated to be a synergy metrics for chemotherapy effectiveness and prognostic significance in invasive breast cancer

Parameters Sample CPN1 x2 P value
Low High
Age (years) ≤ 60 77 53 24 2.851 0.091
 > 60 46 23 23   
Tumor size (cm) ≤ 5 103 67 36 4.325 0.038*
 > 5 20 9 11   
LN metastasis N0 61 38 23 3.031 0.082
 N1 62 24 38   
TNM stage I–II 71 49 22 5.083 0.024*
 III–IV 52 26 26   
 Histological grade I–II 66 48 18 4.389 0.036*
 III 57 32 45   
ER score ≤ 4 66 39 27 10.557 0.228
 > 4 57 37 20   
PR score ≤ 4 91 58 33 12.553 0.128
 > 4 32 18 14   
HER2 score ≤ 4 66 47 19 9.503 0.302
 > 4 57 29 28   
KI67 score ≤ 4 94 57 37 10.8 0.213
 > 4 29 19 10   
P53 score ≤ 4 77 47 30 7.97 0.436
 > 4 46 29 17   
  1. *Statistically significant (P < 0.05)