Fig. 9

The role of Ang II and candesartan on the occurrence and development of mouse HCC. A Schematic diagram of the animal experimental study. B Differences in intraperitoneal tumor size, liver appearance and pathological structure after different drug interventions during the preparation of mouse HCC in situ model (HE magnification,  × 100). C The changes of liver index of mice in different medication groups at different stages of HCC model. Liver index = liver weight (g)/mouse body weight (g) × 100%. *P < 0.05, **P < 0.01 VS control group; ^#P < 0.05 VS HepG2 + candesartan group