Fig. 4

Differentially expressed motifs between the IL-6 group and the Lob group. a Twenty-three conserved motifs (specifically, 22 p-Ser motifs and 1 p-Thr motif) were identified and enriched among the phosphosites. The vertical bars represent the percentage of the specific motif relative to the total number of identified differentially expressed motifs between the two groups. b High-scoring motifs differentially expressed between the IL-6 group and the Lob group. Four motifs (-RxxSP-, -SP-, SPK-, and -SPxxK-) were upregulated in the IL-6 group; five motifs (SDDE-, -SDxE, -SPxR-, -RxxSxE-, and -SPE-) were downregulated. Three motifs (-RxxSP-, -SP-, and SPK-) were identified as enriched in both the upregulated and downregulated phosphosites