Fig. 7

Lactate inhibits the expression of miR-30a and upregulates DBF4 in GC cells. MGC-803 and AGS cells were stimulated with lactate (50 mM) and IL-6 (20 ng/mL) for 24 h. A The expression of miR-30a in MGC-803 cells (left) and AGC cells (right) was detected by qRT-PCR. B The qRT-PCR was used to detect DBF4 mRNA expression in MGC-803 cells (left) and AGC cells (right). Data are presented as the mean ± SD (n = 3). ^*P < 0.05, ^**P < 0.01