Fig. 1
From: CircRFX3 contributes to glioma progression through the circRFX3-miR-1179/miR-1229-VASP axis
CircRFX3 was upregulated in glioma tissues and cells. A and B The expression level of circRFX3 in glioma tissues, glioma cells (A172, U251, SHG44 and LN229) and normal tissues and cells (NHA) was determined by qRT-PCR assay. C The overall survival of glioma patients was analyzed using Kaplan–Meier curve according to circRFX3 level. D and E The association between the overall survival of glioma patients in IDH-MUT/IDH-WT groups and circRFX3 level was analyzed. F After A172 and U251 cells were exposed to Actinomycin D for 0, 8, 16 and 24 h, the levels of circRFX3 and RFX3 in A172 and U251 cells were measured by qRT-PCR assay. G After total RNA in A172 and U251 cells was treated with or without RNase R, circRFX3 and RFX3 levels were determined by qRT-PCR assay. **P < 0.01, ***P < 0.001