Table 2 Difference of gene and pathway mutations with significance between iCAFs high and low groups of TCGA BLCA patients
Gene | iCAFs high-wild | iCAFs High-mutation | iCAFs Low-wild | iCAFs Low-mutation | p-value |
|---|---|---|---|---|---|
FGFR3 | 190 (96.45%) | 7 (3.55%) | 158 (77.45%) | 46 (22.55%) |  < 0.001 |
TP53 | 103 (52.28%) | 94 (47.72%) | 136 (66.67%) | 68 (33.33%) | 0.005 |
Pathways | iCAFs high-affected | iCAFs high-not affected | iCAFs low-affected | iCAFs low-not affected | p-value |
|---|---|---|---|---|---|
TP53 | 112 (56.85%) | 85 (43.15%) | 152 (74.51%) | 52 (25.49%) | < 0.001 |
RTK-RAS | 106 (53.81%) | 91 (46.19%) | 86 (42.16%) | 118 (57.84%) | 0.025 |