Fig. 1

A Consensus map of NMF clustering; B cophenetic distribution having rank = 2–10, where cophenetic correlation is obtained from the consistency matrix proposed by Brunet et al. that is reflective of the stability of the cluster obtained from NMF. The value is between 0 and 1, where a larger value signified a more stable cluster; C the rss distribution with rank = 2–10. Rss is the residual sum of squares and shows clustering performance of a model, where a smaller value yielded a better clustering effect of the model in contrast to the theoretical concept that the smallest value is attained when each sample is clustered into one class; D overall survival (OS) time prognosis survival curve of LIHC molecular subtypes; E DSS time prognosis survival curve of LIHC molecular subtypes