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Fig. 6 | Cancer Cell International

Fig. 6

From: Characterization of a novel glucocorticoid-resistant human B-cell acute lymphoblastic leukemia cell line, with AMPK, mTOR and fatty acid synthesis pathway inhibition

Fig. 6

Expression of proteins associated with GC resistance in NALM-6/HDR. a Cells extracts were analyzed by western blotting for GR and p-GR (Ser211). β-Actin was used as an internal control. Bar graphs show the ratio of proteins to β-Actin. For all experiments, values of triplicate experiments are shown as the mean ± SD. *: p < 0.01 versus NALM-6 and NALM-6/H. #: p < 0.01 versus NALM-6 and NALM-6/HDR. b Cells extracts were analyzed by western blotting for 4E-BP1, p-4E-BP1 (Thr37/46), p70S6K, and p-p70S6K (Thr389). β-Actin was used as an internal control. Bar graphs show the ratio of proteins to β-Actin. For all experiments, values of triplicate experiments are shown as the mean ± SD. *: p < 0.01 versus NALM-6 and NALM-6/H. #: p < 0.01 versus NALM-6 and NALM-6/HDR

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