Fig. 9
From: Prognostic value and immune infiltration of novel signatures in colon cancer microenvironment
Construction of the H19 ceRNA network based on TCGA database. A Flow chart of constructing the H19-miRNA-mRNA network. Two H19-miRNA pairs and five miRNA-mRNA pairs were finally identified, and the network was visualized by Cytoscape software. B Prognostic analysis of five mRNAs in the ceRNA network. This result shows that the expression of CCND1 and VEGFA is significantly related to the survival prognosis of colon cancer. C Correlation analysis between mRNA (CCND1 and VEGFA) expression and six immune cell infiltration levels based on the TIMER database. D Gene set enrichment analysis for H19 expression. The results showed that patients with high H19 expression were mainly concentrated in ABC transporters. Patients with low H19 expression were mainly concentrated in the renin angiotensin system and adipocytokine signaling pathway. Downregulated miRNA (DRmiRNA), Upregulated mRNA (URmRNA)