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Table 1 Association between MAD2L1 and CCNB2 protein expression and patient clinical characteristics

From: Bioinformatics prediction and experimental verification identify MAD2L1 and CCNB2 as diagnostic biomarkers of rhabdomyosarcoma

Patient characteristics

n (%)

MAD2L1

P-value

CCNB2

P-value

Low expression, n (%)

High expression, n (%)

Low expression, n (%)

High expression, n (%)

Gender

 Male

21 (63.6)

9 (42.9)

12 (57.1)

0.457

8 (38.1)

13 (61.9)

0.259

 Female

12 (36.4)

3 (25)

9 (75)

 

2 (16.7)

10 (83.3)

 

Age (years)

 ≤ 5

7 (21.2)

5 (71.4)

2 (28.6)

0.071

4 (57.1)

3 (42.9)

0.161

 > 5

26 (78.8)

7 (26.9)

19 (73.1)

 

6 (23.1)

20 (76.9)

 

Tumor diameter

 ≤ 5 cm

11 (33.3)

4 (36.4)

7 (63.6)

1.000

8 (72.7)

3 (27.3)

0.000a

 > 5 cm

22 (66.7)

8 (36.4)

14 (63.6)

 

2 (9.1)

20 (90.9)

 

Histology

 ERMS

14 (42.4)

7 (50)

7 (50)

0.427

5 (35.7)

9 (64.3)

0.164

 ARMS

12 (36.4)

3 (25)

9 (75)

 

5 (41.7)

7 (58.3)

 

 PRMS

7 (21.2)

2 (28.6)

5 (71.4)

 

0 (0.0)

7 (100.0)

 

Location

 Head and neck

9 (27.3)

3 (33.3)

6 (66.7)

1.000

4 (44.4)

5 (55.6)

0.943

 Torso and limbs

16 (48.5)

6 (37.5)

10 (62.5)

 

5 (31.3)

11 (68.7)

 

 Urinary

5 (15.2)

2 (40)

3 (60)

 

2 (40)

3 (60)

 

 Abdominal or retroperitoneal

3 (9)

1 (33.3)

2 (66.7)

 

1 (33.3)

2 (66.7)

 
  1. P < 0.05 indicates a significant association among the variables
  2. aSignificant difference