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Fig. 1 | Cancer Cell International

Fig. 1

From: HPV E6/E7 mRNA in situ hybridization in endocervical adenocarcinoma: implications for prognosis and diagnosis

Fig. 1

Representative images of human papillomavirus (HPV) E6/E7 RNAscope in paraffin-embedded endocervical adenocarcinoma (ECA) samples. A HPV mRNA was detected using RNAscope in ECA (T) and non-tumorous tissues adjacent to ECA (N). Representative images of scores 0 (T0), 1 (T1), 2 (T2), 3 (T3) and 4 (T4) are shown. B The proportion of RNAscope scores in ECA tissues. C Positive rates of HPV by PCR, RNAscope, HPV genotype and p16 IHC. (D) Receiver operating characteristics curve for HPV, detected by PCR, immunohistochemistry, genotyping and RNAscope for HPV-associated vs. non-HPV-associated types

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Cancer Cell International

ISSN: 1475-2867

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