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Fig. 4 | Cancer Cell International

Fig. 4

From: The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression

Fig. 4

MiR-330-3p was downregulated in HCC tissues in a manner correlated with HCC prognosis. a Schematic illustration of overlapping potential target miRNAs of circSLC7A11, as predicted by the Starbase and Circinteractome online tools. b Relative expression of candidate miRNAs in transfected HCCLM3 and Hep3B cells. c Relative expression of miR-330-3p in HCC tissues and paired adjacent tissues T, tumor (n = 93); N, non-tumor (n = 93) (p = 0.001). d Box plot of miR-330-3p expression in The Cancer Genome Atlas (TCGA) HCC tumors and paired normal liver tissues. e Relative expression of miR-330-3p in HCC cell lines relative to the immortalized hepatocyte cell line WRL68. Data are means ± SD (ns = not significant, *p < 0.05; **p < 0.01; ***p < 0.001). f Survival curves for HCC patients showing low and high miR-330-3p expression (n = 93, p = 0.0023)

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Cancer Cell International

ISSN: 1475-2867

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