Fig. 3
From: CircTUBGCP3 facilitates the tumorigenesis of lung adenocarcinoma by sponging miR-885-3p
Restored expression of circTUBGCP3 promoted the proliferation, colony formation and invasion of LAC cells. A qPCR analysis of the expression levels of circTUBGCP3 in multiple LAC cell lines. B qPCR analysis of the efficiency of plasmids-mediated circTUBGCP3 in A549 and SPC-A1 cell lines or lentivirus-mediated si-circTUBGCP3 in NCI-H460 cell line. C, D MTT analysis of the cell viability after the transfection with circTUBGCP3 plasmids in A549 and SPC-A1 cell lines or si-circTUBGCP3 in NCI-H460 cell line. E, F Colony formation analysis of the colony formation capabilities after the transfection with circTUBGCP3 plasmids in A549 and SPC-A1 cell lines or si-circTUBGCP3 in NCI-H460 and NCI-H1299 cell lines. G, H Transwell analysis of the cell invasive potential after the transfection with circTUBGCP3 plasmids in A549 and SPC-A1 cell lines or si-circTUBGCP3 in NCI-H460 and NCI-H1299 cell line. Data are the means ± SEM of three experiments. *P < 0.05, **P < 0.01, ***P < 0.001