Fig. 2

Morphological features. Transmission electron microscopy of BJeLR cells treated with DMSO (10 h), erastin (37 mM, 10 h), staurosporine (STS, 0.75 mM, 8 h), H₂O₂ (16 mM, 1 h), and rapamycin (Rap, 100 nM, 24 h). Single white arrowheads, shrunken mitochondria; paired white arrowheads, chromatin condensation; black arrowheads, cytoplasmic and organelle swelling and plasma membrane rupture; black arrow, formation of double-membrane vesicles. A minimum of 10 cells per treatment condition were examined