Fig. 6
From: FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma
The FOXM1-TYMS axis regulated the growth of HCC cells and mediated the resistance of cells to 5-FU. A CCK-8 assays, B flow cytometry apoptosis assays in HepG2 and HuH-7 cells transfected with FOXM1-OE or FOXM1-OE plasmid + shTYMS or negative control. C CCK-8 assays in HepG2 and HuH-7 cells transfected with FOXM1-OE plasmid or FOXM1-OE plasmid + shTYMS or negative control. All cells were treated with 5-FU at indicated concentrations for 24 h. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001