AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease

Table 1 Clinicopathological characteristics of all patients

Unique ID	Age (year)	Gender	Nephrectomy type	Creatinine	Primary tumor status	Tumor size (mm)	Fuhrmann grade	Leibovich score 2003^a	Leibovich score 2018^b	Time to metastasis (days)	Pair ID
Rcc9	51	Female	Radical	58	T1a	38	3	2	5	1544	1
Rcc8	63	Male	Radical	60	T1a	40	3	1	3	1994	2
Rcc3	66	Male	Radical	113	T1a	35	3	1	3	2632	3
Rcc11	66	Male	Partial	61	T1a	15	3	2	5	965	4
Rcc1	72	Female	Radical	106	T1a	20	2	0	2	2680	5
Rcc2	72	Male	Radical	109	T1b	50	2	2	5	2319	6
Rcc5	83	Male	Radical	81	T1b	50	2	2	5	109	7
Rcc6	67	Male	Radical	176	T1b	48	2	2	5	1385	8
Rcc13	34	Male	Partial	73	T1a	23	3	1	3		1
Rcc24	47	Female	Partial	48	T1a	40	3	1	3		1
Rcc17	54	Male	Partial	68	T1a	35	3	1	3		2
Rcc20	66	Male	Radical	67	T1a	30	3	1	3		2
Rcc21	57	Male	Partial	73	T1a	30	3	1	3		3
Rcc16	62	Male	Radical	82	T1a	30	3	1	3		3
Rcc23	74	Male	Partial	81	T1a	16	3	1	3		4
Rcc22	66	Male	Partial	83	T1a	38	3	1	3		4
Rcc10	78	Female	Partial	64	T1a	20	2	0	2		5
Rcc18	68	Female	Partial	45	T1a	20	2	0	2		5
Rcc14	72	Male	Partial	97	T1b	55	2	2	5		6
Rcc4	63	Male	Radical	82	T1b	50	2	2	5		6
Rcc7	76	Male	Radical	98	T1b	45	2	2	5		7
Rcc15	75	Male	Radical	73	T1b	45	2	2	5		7
Rcc12	63	Male	Radical	80	T1b	45	2	2	5		8
Rcc19	68	Male	Radical	68	T1b	45	2	2	5		8

Clinicopathological characteristics of progressor (n = 8) and nonprogressor (n = 16) patients. Nonprogressors were matched 2:1 to progressors for sex, age, primary tumor stage and size, Fuhrman grade, and eGFR. Pair-ID refers to matched nonprogressors and progressors. No patients exhibited tumor thrombus, sarcomatoid differentiation, or constitutional symptoms. Patients with distant metastases that were not treatment naïve, had lymph node metastasis, suffered from heart failure (grade ≥ 3 according to the New York Heart Association Classification), or used immunosuppressive drugs due to transplantation or severe rheumatic disease at the time of the biopsy were excluded from the study
^aScoring was performed according to the 2003
^bScoring was performed according to the 2018 Score

ISSN: 1475-2867