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Fig. 1 | Cancer Cell International

Fig. 1

From: Imperatorin induces autophagy and G0/G1 phase arrest via PTEN-PI3K-AKT-mTOR/p21 signaling pathway in human osteosarcoma cells in vitro and in vivo

Fig. 1

IMP depressed the proliferation, invasion and migration of human osteosarcoma cells. A Chemical structure of IMP. B IMP inhibited the proliferation of 143B and U2OS cells in a dose-dependent and time-dependent manner. IMP repressed the migration of 143B (C) and U2OS (D) cells in a dose-dependent manner. IMP inhibited the invasion of 143B (E) and U2OS (F) cells in a dose-dependent manner. IMP inhibited colony formation of 143B (G) and U2OS (H) cells in a dose-dependent manner. Scale bars equaled 200 μm. *p  < 0.05; **p  < 0.01; ***p  < 0.001, one-way ANOVA; data were mean  ±  SD

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Cancer Cell International

ISSN: 1475-2867

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