Fig. 5

The chronic inflammation degree is relevant to esophageal histological severeness. A Representative images expressing normal epithelium without evident inflammation, B hyperplastic epithelium with mild inflammation, C low-grade intra-epithelial neoplasia epithelium with deep inflammation, D high-grade intra-epithelial neoplasia epithelium with severe inflammation. Representative images showing normal esophageal epithelium and esophageal epithelial hyperplasia transition zone (E), esophageal intra-epithelial neoplasia and normal esophageal epithelial transition zone (F). G Representative images showing esophageal intraepithelial neoplasia and normal esophageal epithelial transition zone, with the increase in the expression of CD98hc, the level of inflammation in the lamina propria increases. Scale bar represents 100 μm