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Table 6 comparison of the efficiency of Viral and non-viral transduction methods

From: NK cell upraise in the dark world of cancer stem cells

Source of NK cells

Transduction method

Transduction vector

Transduction efficiency (%)

References

Primary cells

Viral-based

Lentivirus

16–80

[111, 118]

retrovirus

27–75

[119]

Non-viral based

mRNA transfection

10–85

[120, 121]

Trogocytosis

24–47

[122]

Cell lines

NK-92

Viral-based

Lentivirus

15–26

[121, 123, 124]

Non-viral based

mRNA transfection

56

[121]

PiggyBac

84

[111]

YTS

Viral-based

Lentivirus

30–98

[111]

LNK

30–40

[124]

DERL7

30–40

UCB-derived Cells

Viral-based

Lentivirus

12–73

[121]

retrovirus

49–67

[125, 126]

iPSCs

Non-viral based

pKT2-mCAG-IRES

–

[127, 128]

PiggyBac