Table 2 Transplantation details
Conditioning regime | P-ALG (N = 28) | R-ATG (N = 63) | P value |
|---|---|---|---|
Flu, CY, P-ALG ± Bu | Flu, CY, R-ATG ± Bu | ||
Graft source | |||
 PBSC | 24 (85.7%) | 47 (74.6%) | 0.237 |
 PBSC + BM | 4 (14.3%) | 16 (25.4%) | |
Donor-recipient bloodtype match | |||
 Matched | 14 (50.0%) | 34 (54.0%) | 0.627 |
 Major mismatched | 7 (25.0%) | 9 (14.3%) | |
 Minor mismatched | 4 (14.3%) | 13 (20.6%) | |
 Bidirectional mismatch | 3 (10.7%) | 7 (11.1%) | |
Donor-recipient gender match | |||
 Female to female | 3 (10.7%) | 9 (14.3%) | 0.256 |
 Female to male | 5 (17.9%) | 15 (23.8%) | |
 Male to female | 12 (42.9%) | 14 (22.2%) | |
 Male to male | 8 (28.6%) | 25 (39.7%) | |
Donor-recipient HLA match | |||
 5/10 | 15 (53.6%) | 32 (50.8%) | 0.108 |
 6/10 | 3 (10.7%) | 14 (22.2%) | |
 7/10 | 1 (3.6%) | 10 (15.9%) | |
 8/10 | 4 (14.3%) | 4 (6.3%) | |
 9/10 | 3 (10.7%) | 2 (3.2%) | |
 10/10 | 2 (7.1%) | 1 (1.6%) | |
GVHD prophylaxis | |||
 CSA + MTX | 22 (78.6%) | 45 (71.4%) | 0.475 |
 FK506 + MTX | 6 (21.4%) | 18 (28.6%) | |
Donor-recipient CMV serostatus | |||
 D+/R+ | 21 (95.5%) | 54 (98.2%) | 0.492 |
 D−/R+ | 1 (4.5%) | 1 (1.8%) | |
 D+/R− | 0 | 0 | |
 D−/R− | 0 | 0 | |
Donor age (years) | |||
 Median (range) | 34 (9–54) | 36 (8–62) | 0.447 |
Dose of MNC (× 108/kg) | |||
 Median (range) | 10.66 (5.08–22.68) | 9.37(6.00–25.49) | 0.411 |
Dose of CD34+ cells(× 106/kg) | |||
 Median (range) | 3.44 (2.02–8.60) | 3.25 (1.59–7.35) | 0.827 |