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Table 3 Outcomes of patients

From: Comparison of porcine ALG and rabbit ATG on outcomes of HLA-haploidentical hematopoietic stem cell transplantation for patients with acquired aplastic anemia

Outcomes

P-ALG (N = 28)

R-ATG (N = 63)

P value

Time of engraftment

 ANC, days (range)

11 (10–22)

13 (10–23)

0.294

 PLT, days (range)

12.5 (8–95)

15 (10–83)

0.465

Infection

 CMV

  Yes

13 (46.4%)

45 (71.4%)

0.022

  No

15 (53.6%)

18 (28.6%)

 EBV

  Yes

1 (3.6%)

16 (25.4%)

0.014

  No

27 (96.4%)

47 (74.6%)

 IFD

  Yes

1 (3.6%)

6 (9.5%)

0.577

  No

27 (96.4%)

57 (90.5%)

 Severe bacterial infection

  Yes

5 (17.9%)

16 (25.4%)

0.431

  No

23 (82.1%)

47 (74.6%)

 Graft rejection

  Yes

0 (0%)

6 (9.5%)

0.218

  No

28 (100%)

57 (90.5%)

GVHD

 aGVHD, %

65.39 ± 9.33

62.71 ± 6.30

0.653

 II–IV aGVHD, %

38.46 ± 9.54

35.64 ± 6.24

0.695

 III–IV aGVHD, %

19.23 ± 7.73

10.53 ± 4.07

0.291

 cGVHD, %

22.22 ± 12.25

22.31 ± 6.30

0.915

 Moderate-severe cGVHD, %

5.56 ± 5.40

9.28 ± 4.46

0.993

 5-year OS, %

74.83 ± 8.24

72.29 ± 6.26

0.830

 5-year GFFS, %

71.05 ± 8.65

62.71 ± 6.22

0.662

 5-year FFS, %

74.83 ± 8.24

66.09 ± 5.84

0.647

 5-year TRM, %

25.17 ± 8.24

26.29 ± 6.22

0.708