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Fig. 2 | Cancer Cell International

Fig. 2

From: FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis

Fig. 2

High FTH expression is linked to high risk and poor prognosis in HCC. A, B mRNA expressions of FTH1 were discovered to be overexpressed in primary hepatocellular carcinoma tissues compared to adjacent normal tissues using GEPIA and UALCAN databases. C Higher mRNA expression of FTH1 was associated with shorter OS in hepatocellular carcinoma patients (GEPIA database). D The overall survival in a cohort of 593 hepatocellular carcinoma patients was analyzed by univariate analysis. E, F The association of FTH1 expression with cancer stages and tumor grades (TCGA samples). G The level of serum ferritin in the indicated groups was determined. (Values are represented as mean ± SD. P < 0.05, P < 0.01, P < 0.001 versus indicated groups)

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