Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis

Fig. 6

FTH rescues the impaired mitochondrial homeostasis upon ferroptosis. A Control or FTH overexpression HCCLM3 cells were treated with cystine-free medium, then stained by mitoTracker-Red and JC-10. The morphological changes of mitochondria and JC-10 fluorescence intensities were observed under confocal microscope (Scale bars 10 μm). B Control and FTH ectopic expression cells were treated with cystine-free medium for 8 h, the mitochondrial oxygen consumption rate (OCR) was monitored by Seahorse analyzer. CF The OCR values of maximal respiration, ATP production, spare respiratory capacity, and non-mitochondrial respiratory were calculated. (Values are represented as mean ± SD. P < 0.05, P < 0.01 versus indicated groups)

Back to article page