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Table 2 Expression status of selected genes with diagnostic or prognostic value in human and canine prostate cancer in the analyzed cell lines compared to original tumor tissues

From: RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures

Gene

Ensembl gene ID

PAC

PAC metastasis

TCC

Hormonal receptors and genes associated with androgen-independence

 AR

ENSCAFG00000016656

n.e

n.e

n.e

 ESR1

ENSCAFG00000000430

e.

e.

e.

 ESR2

ENSCAFG00000015846

n.e

n.e

n.e

 PGR

ENSCAFG00000003978

e.

e.

e.

 AURKA

ENSCAFG00000029331

e.

e.

e.

 HSD3B2

ENSCAFG00000010039

n.e

n.e

n.e

 HNF1A

ENSCAFG00000010502

e.

e.

e.

 HNF4G

ENSCAFG00000008285

e.

e.

e.

 MYCN

ENSCAFG00030012614

n.e

n.e

n.e

 SPINK1

ENSCAFG00000006647

n.e

n.e

n.e

Prostate-specific markers

 KLK2

ENSCAFG00000002907

n.e

n.e

n.e

 NKX3-1

ENSCAFG00000009107

n.e

n.e

n.e

 ACPP

ENSCAFG00040021029

Down

Down

e

 FOLH1

ENSCAFG00000024888

Down

Down

e

 TP63

ENSCAFG00000013961

e.

e.

e.

 AMACR

ENSCAFG00000018831

e.

e.

e.

 FASN

ENSCAFG00000006006

e.

e.

e.

 SLC45A3

ENSCAFG00030008817

e.

e.

e.

 PSCA

ENSCAFG00000032433

Down

Down

e.

 GSTP1

ENSCAFG00000011349

Down

Down

e.

 HOXB13

ENSCAFG00000016870

Up

Up

e.

 GOLM1

ENSCAFG00000001350

Up

Up

e.

  1. e., expressed at non-negligible levels, but not differentially expressed; n.e., not expressed; up/down, up- or downregulated in the cell lines of the respective histopathological classification