Fig. 4
From: Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway
Bioinformatics analysis based on TCGA and GEO datasets reveals a link between ANXA1 and EGFR signaling in BLCA. A Heatmaps showing 30 proteins significantly differentially expressed in the high ANXA1 and low ANXA1 protein expression groups from the TCGA dataset. B Individual value plot showing the protein expression of EGFR between the high and low ANXA1 groups in the TCGA dataset. C Pearson correlation analysis of ANXA1 and EGFR protein expression (RPPA) in the TCGA dataset. D, E Pearson correlation analysis of ANXA1 and EGFR gene expression in TCGA and GEO datasets. F–I GSEA analysis of EGF/EGFR, PI3K/AKT, ERK and JAK/STAT signaling in high and low ANXA1 samples based on the TCGA dataset