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Fig. 1 | Cancer Cell International

Fig. 1

From: Construction of a risk prediction model using m6A RNA methylation regulators in prostate cancer: comprehensive bioinformatic analysis and histological validation

Fig. 1

Characteristics of m6A regulators in prostate cancer. A (top) The CNV variation frequency of m6A regulators in TCGA-PRAD. Blue dot: deletion frequency; red dot: amplification frequency. (bottom) The location of CNV alterations of m6A regulators on 23 chromosomes. Blue dot: copy number loss, red dot: copy number gain. B Box plot of the expression of the 25 m6A regulators in PCa and normal tissues. Median values ± interquartile ranges are shown in the graph. ns P > 0.05; * P < 0.05; ** P < 0.01; ***P < 0.001. C The mutation frequency of 25 m6A regulators in 484 TCGA-PRAD patients is shown on the waterfall plot. Columns represent individual patients, the upper bar plot shows the TMB, the right bar plot shows the proportion of each variant type, and the stacked bar plot below shows the transformed fraction of each patient

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Cancer Cell International

ISSN: 1475-2867

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