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Table 2 The expression levels of 25 m6A regulators in TCGA-PRAD and normal tissues

From: Construction of a risk prediction model using m6A RNA methylation regulators in prostate cancer: comprehensive bioinformatic analysis and histological validation

Gene

Normal (median)

Tumor (median)

P value

P symbola

METTL3

4.304684

4.790198

2.44E-11

***

METTL14

3.851525

3.682336

0.03669

*

METTL16

4.198874

3.963548

0.023015

*

WTAP

5.979951

5.95777

0.740731

ns

VIRMA

4.214773

4.064446

0.255423

ns

ZC3H13

5.0224

4.529186

4.93E-08

***

RBM15

2.901797

2.98326

0.025136

*

RBM15B

5.183314

5.548273

2.44E-09

***

CBLL1

4.733786

4.543428

0.15531

ns

YTHDC1

5.389822

5.331527

0.261206

ns

YTHDC2

3.509213

3.550773

0.057348

ns

YTHDF1

5.819509

6.009969

0.000426

***

YTHDF2

5.58442

5.729154

0.000836

***

YTHDF3

5.628178

5.457101

0.396418

ns

HNRNPC

7.307854

7.455818

0.008174

**

FMR1

4.07059

3.89702

0.002945

**

LRPPRC

5.580982

5.53787

0.397438

ns

HNRNPA2B1

7.831312

8.167939

3.34E-10

***

IGFBP1

0

0

0.187698

ns

IGFBP2

6.997535

7.466738

7.00E-07

***

IGFBP3

6.508928

5.863846

7.73E-05

***

RBMX

6.32992

6.408794

0.0266

*

ELAVL1

5.323377

5.421104

0.000426

***

FTO

3.998101

3.576431

1.24E-07

***

ALKBH5

7.08196

6.930204

0.003862

**

  1. a ns P > 0.05; * P < 0.05; ** P < 0.01; ***P < 0.001