Table 7 Expression of m6A regulators among three geneClusters
Gene | Group A (median) | Group B (median) | Group C (median) | P value | P symbola |
|---|---|---|---|---|---|
METTL3 | 25.43239 | 28.121 | 27.4013 | 0.067214 | ns |
METTL14 | 12.49848 | 11.61563 | 10.65721 | 0.002169 | ** |
METTL16 | 15.11261 | 14.27289 | 14.50079 | 0.198853 | ns |
WTAP | 59.59774 | 61.67926 | 63.11492 | 0.011085 | * |
VIRMA | 17.50783 | 14.85196 | 13.20034 | 5.68E-09 | *** |
ZC3H13 | 24.27743 | 19.83391 | 16.76071 | 9.62E-06 | *** |
RBM15 | 7.196895 | 6.848082 | 6.450624 | 0.001906 | ** |
RBM15B | 50.11591 | 45.15223 | 37.2346 | 1.84E-09 | *** |
CBLL1 | 21.41409 | 24.31778 | 19.51026 | 0.001104 | ** |
YTHDC1 | 41.63361 | 37.73905 | 36.59234 | 7.15E-07 | *** |
YTHDC2 | 11.26867 | 10.11635 | 8.712406 | 1.55E-06 | *** |
YTHDF1 | 65.1071 | 63.04105 | 58.22785 | 0.027657 | * |
YTHDF2 | 55.0904 | 51.34166 | 48.46479 | 0.00317 | ** |
YTHDF3 | 47.39185 | 42.42069 | 33.32456 | 6.17E-08 | *** |
HNRNPC | 187.0431 | 166.5035 | 152.1311 | 2.12E-08 | *** |
FMR1 | 15.0888 | 13.23247 | 12.25827 | 1.79E-07 | *** |
LRPPRC | 53.01479 | 43.53207 | 37.2318 | 1.07E-08 | *** |
HNRNPA2B1 | 299.7436 | 280.6586 | 271.21 | 0.001427 | ** |
IGFBP1 | 0 | 0 | 0 | 0.057215 | ns |
IGFBP2 | 133.3923 | 214.2155 | 266.8425 | 2.11E-25 | *** |
IGFBP3 | 66.44944 | 43.65073 | 48.12219 | 4.87E-08 | *** |
RBMX | 92.67909 | 79.35541 | 72.55706 | 1.94E-12 | *** |
ELAVL1 | 44.32754 | 41.28624 | 39.84319 | 0.000294 | *** |
FTO | 11.70362 | 10.25875 | 7.217273 | 7.92E-09 | *** |
ALKBH5 | 122.1352 | 121.0671 | 118.568 | 0.116104 | ns |