Fig. 1

miR-937-3p is associated with LUAD metastasis. A The volcano plot shows the difference between miRNAs in the tissues of healthy individuals and LUAD patients in the TCGA database. The miRNAs were classified based on fold change (log2fc) between the two groups. B The relationship between miR-937-3p and the survival of lung cancer patients (n = 131 in the miR-937-3p-low group and n = 373 in the miR-937-3p-high group). C The miR-937-3p expression level in NSCLC cell lines and paired 16HBE was investigated by qRT-PCR. D The miR-937-3p expression level in 60 NSCLC tissues and paired adjacent tissues was investigated by qRT-PCR. E ISH for miR-937-3p in tumor tissue and corresponding paracancerous tissues. F qRT-PCR analysis of miR-937-3p expression in primary LUAD tissues with or without metastasis and adjacent tissues (25 adjacent,25 without metastasis and 25 with metastasis). G ISH for miR-937-3p in primary LUAD tissues with or without metastasis and adjacent tissues. The data are represented as mean ± SD. (*P < 0.05; **P < 0.01; ***P < 0.001)