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Fig. 4 | Cancer Cell International

Fig. 4

From: MiR-937-3p promotes metastasis and angiogenesis and is activated by MYC in lung adenocarcinoma

Fig. 4

SOX11 overexpression reversed the effect of miR-937-3p on the malignant progress of LUAD cells. A After co-transfection and the expression level of SOX11 was detected by qRT-PCR. B The roles of promoting angiogenesis of miR-937-3p was attenuated by high expression of SOX11; scale bars, 100 μm. C, D Transwell assays and wound-healing assay detected that SOX11 attenuated the inhibitory effects of miR-937-3p; scale bars, 200 μm. E, F The expression levels of SOX11 protein and AKT pathway related proteins after SOX11 plasmid transfection were analyzed by Western blotting in co-transfected cell lines. 1: miR-NC;2: miR-NC+SOX11;3: miR-937-3p;4: miR-937-3p+SOX11; The data expressed as the mean ± SD. (*P < 0.05;**P< 0.01; ***P < 0.001)

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