Fig. 5
Characteristics of immune signatures with m6A regulators and risk score patterns. A Heatmap shows the enrichment of 29 immune signatures in two risk score groups. Immunity cluster, tumor purity, ESTIMATE score, immune score, and stromal score were used as patient annotations. B The proportion of patients from different immunity clusters in low and high risk groups. C–F Violin plot shows the different status of scores in risk score groups. Stromal score (C), immune score (D), tumor purity (E), and ESTIMATE score (F). G The association of insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) expression levels with 6 immune cells and the tumor purity. The data was obtained from the Tumor Immune Estimation Resource (TIMER) website (https://cistrome.shinyapps.io/timer/). H The association of m6A regulators mutations with 6 immune cells. The data was obtained from the TIMER website (https://cistrome.shinyapps.io/timer/). I The association between m6A regulators in risk score patterns with immune checkpoints. Red at the bottom right corner represents the positive correlation, and yellow represents the negative correlation. Yellow also represents statically difference at the top left corner. *P < 0.05, **P < 0.01, ***P < 0.001