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Fig. 1 | Cancer Cell International

Fig. 1

From: DNA methyltransferase 1 inhibits microRNA-497 and elevates GPRC5A expression to promote chemotherapy resistance and metastasis in breast cancer

Fig. 1

Expression of DNMT1 and miR-497 in breast cancer tissues was examined. A The expression of DNMT1 in 1097 breast cancer samples and 114 adjacent normal tissue samples (left), and expression of miR-497 in 749 breast cancer samples and 76 adjacent normal tissue samples (right) collected in TCGA database. The x-axis represented sample type, the y-axis expression value, and the blue box diagram normal samples. Normal samples were shown in blue box and tumor samples shown in red box. B The expression of DNMT1 and miR-497 in breast cancer tissues and adjacent normal tissues from 42 patients with breast cancer detected by RT-qPCR. C, Pearson correlation analysis adopted to detect the correlation between DNMT1 and miR-497 expression in breast cancer tissues. *p  < 0.05 vs. adjacent normal tissues

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