Fig. 1

mRNA and protein expression of LMNB1 in human cancers. A LMNB1 mRNA expression in diverse human cancers or cancer subtypes was visualized by TIMER2.0 based on TCGA database. The statistical significance was calculated with the Wilcoxon test (*p < 0.05; **p < 0.01; ***p < 0.001). B Total protein level of lamin B1 in the tumor tissues and corresponding normal tissues of BRCA, COAD, KIRC, LUAD, OV and UCEC in the CPTAC database was compared using UALCAN. Significance of difference was evaluated by Student’s t test. C mRNA expression of LMNB1 was analyzed in different pathological stages in TCGA cancers. One-way ANOVA was performed to estimate the significance of LMNB1 expression in different groups