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Fig. 3 | Cancer Cell International

Fig. 3

From: ERBB3 binding protein 1 promotes the progression of malignant melanoma through activation of the Wnt/ β-catenin signaling pathway

Fig. 3

Knockdown of Ebp1 inhibits proliferation and metastasis of melanoma cells in vitro and in vivo. a The migration capability of A375 and B16 cells were determined via wound-healing experiments (***p < 0.001, vs. shNC). b Effect of Ebp1 on the invasion of melanoma cells by Transwell assay (***p < 0.001, vs. shNC). c Ebp1 knockdown decreases the lung metastasis ability of B16 cells. d Morphological feature of the lung metastasis by H&E staining. e Surface pulmonary metastatic nodules were counted (*p < 0.05, vs. shNC)

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Cancer Cell International

ISSN: 1475-2867

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