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Fig. 1 | Cancer Cell International

Fig. 1

From: Genomic correlates of programmed cell death ligand 1 (PD-L1) expression in Chinese lung adenocarcinoma patients

Fig. 1

Distinct mutational patterns and biomarkers of Chinese lung adenocarcinoma patients grouped by PD-L1 expression. a) The mutational landscape of top 25 mutated genes. PD-L1 expression levels, TMB and HLA LOH status are annotated in the top panel. Associations between PD-L1 expression and immunotherapy related biomarkers including b) TMB, c) TNB, d) CIN and e) HLA LOH. TMB, tumor mutation burden. HLA, human leukocyte antigen. LOH, loss of heterogeneity. TNB, tumor neoantigen burden. CIN, chromosome instability. 'ns', not significant. *P < 0.05, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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