Fig. 2

Associations between gene mutations and PD-L1 expression in Chinese lung adenocarcinoma patients. a) Percentages of mutated genes between PD-L1 high and negative expression groups. Blue dots denote genes associated with significantly differential PD-L1 expression (Q value < 0.25). b) Percentages of mutated genes among different PD-L1 expression groups. c) Percentages of significantly mutated pathways among different PD-L1 expression groups. d) Amplifications and e) deletions between PD-L1 high and negative expression groups. CNVs with Q value < 0.25 were significantly. Red dots denote CNV events only in PD-L1 high group. Blue dots denote CNV events only in PD-L1 negative group. CNVs, copy number variations. *P < 0.05, **P < 0.01, ***P < 0.001