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Fig. 2 | Cancer Cell International

Fig. 2

From: LINC01128 facilitates the progression of pancreatic cancer through up-regulation of LDHA by targeting miR-561-5p

Fig. 2

LINC01128 knockdown inhibited proliferation, migration, invasion, and EMT and induced G2/M phase arrest. a The transfection efficiency of SW1990 and BxPC-3 cells after LINC01128 knockdown by shRNA was analyzed using qRT-PCR. b, c CCK-8 assays and clone formation assays were used to determine the cell proliferation rate and cell viability. d Fluorescence-activated cell sorting (FACS) was used to analyze cell cycle distribution. e, f Cell migration and invasion abilities were analyzed using transwell migration and invasion assays. g The protein expression of E-ceaderin, N-cadherin, Slug, Snail and Vimentin was detected by western blot analysis. Data are presented as mean ± SD of three independent experiments. *p < 0.05, **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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