Table 3 Univariate and multivariate Cox regression analysis of progression-free survival in patients with esophageal squamous cell carcinoma
From: High AKAP8L expression predicts poor prognosis in esophageal squamous cell carcinoma
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Gender (Female vs. Male) | 1.148 (0.680–1.938) | 0.606 |  |  |
Age (< 60 vs. ≥ 60) | 1.936 (1.289–2.908) | 0.001 | 1.737 (1.145–2.633) | 0.009 |
Differentiation grade (III vs. I–II) | 0.851 (0.539–1.344) | 0.490 |  |  |
T stage (T3–4 vs. T1–2) | 1.593 (1.013–2.504) | 0.044 | 1.634 (0.920–2.903) | 0.094 |
N stage (N1–2 vs. N0) | 2.709 (1.788–4.106) |  < 0.0001 | 2.707 (1.355–5.407) | 0.005 |
M stage (M1 vs. M0) | 1.251 (0.545–2.872) | 0.597 |  |  |
Clinical stage (III–IV vs. I–II) | 2.122 (1.413–3.189) |  < 0.0001 | 0.702 (0.324–1.518) | 0.368 |
AKAP8L expression (High vs. Low) | 2.192 (1.449–3.317) |  < 0.0001 | 1.943 (1.258–3.000) | 0.003 |