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Fig. 5 | Cancer Cell International

Fig. 5

From: Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis

Fig. 5

Screen of differential expressed microRNAs (DEmiRNAs) in the plasma-derived exosomes and functional analyses. A The volcano figure showed 680 DEmiRNAs, including 393 upregulated miRNAs and 287 downregulated miRNAs, were identified in the resistant plasma-derived exosomes. The blue points represent the downregulated miRNAs; the grey points represent the normal; the red points represented the upregulated miRNAs. B The top20 Gene Ontology (GO) terms enriched by the identified DE-miRNAs. C The top20 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enriched by the identified DE-miRNAs

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Cancer Cell International

ISSN: 1475-2867

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