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Fig. 2 | Cancer Cell International

Fig. 2

From: Overexpression of CBS/H2S inhibits proliferation and metastasis of colon cancer cells through downregulation of CD44

Fig. 2

Exogenous H2S inhibits CRC cell proliferation and migration. A GYY4137 increases the intracellular levels of H2S in HT-29 cells visualized by H2S fluorescent probe. Scale bar, 20 μm. B GYY4137 inhibits the proliferation of HT-29 and HCT-116 cells assessed by CKK-8 assay (*p < 0.05, ***p < 0.001). C Proliferation capacity remains unimpaired after 18-h of GYY4137 treatment in HT-29 and HCT-116 cells. D, E Migration capacity determined by 18-h transwell assay in HT-29 and HCT-116 cells treated with GYY4137 (**p < 0.01, ***p < 0.001). Scale bar, 100 μm

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Cancer Cell International

ISSN: 1475-2867

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